Atypical Protein Kinase C Promotes its own Asymmetric Localisation by Phosphorylating Cdc42 in Polarising Cells

Atypical protein kinase C (aPKC) is a major regulator of cell polarity. Acting in conjunction with Par6, Par3 and the small GTPase Cdc42, aPKC becomes asymmetrically localised and drives the polarisation of cells. aPKC activity is crucial for its own asymmetric localisation, suggesting a hitherto un...

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Detalles Bibliográficos
Autores principales: Packer, John, Gubieda, Alicia G., Brooks, Aaron, Deutz, Lars N., Squires, Iolo, Ellison, Shona, Naganathan, Sundar Ram, Wollman, Adam J.M., Dickinson, Daniel J., Rodriguez, Josana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10675845/
https://www.ncbi.nlm.nih.gov/pubmed/38009101
http://dx.doi.org/10.1101/2023.10.27.563985

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10675845/
https://www.ncbi.nlm.nih.gov/pubmed/38009101
http://dx.doi.org/10.1101/2023.10.27.563985

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