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Neutralization of extracellular histones by sodium-Β-O-methyl cellobioside sulfate in septic shock

BACKGROUND: Extracellular histones have been associated with severity and outcome in sepsis. The aim of the present study was to assess the effects of sodium-β-O-Methyl cellobioside sulfate (mCBS), a histone-neutralizing polyanion, on the severity and outcome of sepsis in an experimental model. METH...

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Detalles Bibliográficos
Autores principales: Garcia, Bruno, Su, Fuhong, Dewachter, Laurence, Wang, Yong, Li, Ning, Remmelink, Myriam, Eycken, Marie Van, Khaldi, Amina, Favory, Raphaël, Herpain, Antoine, Moreau, Anthony, Moiroux-Sahraoui, Alexander, Manicone, Francesca, Annoni, Filippo, Shi, Lin, Vincent, Jean-Louis, Creteur, Jacques, Taccone, Fabio S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10675855/
https://www.ncbi.nlm.nih.gov/pubmed/38001494
http://dx.doi.org/10.1186/s13054-023-04741-x