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Cancer-associated fibroblasts-derived CXCL12 enhances immune escape of bladder cancer through inhibiting P62-mediated autophagic degradation of PDL1

BACKGROUND: Cancer-associated fibroblasts (CAFs), the predominant stromal cell of tumor microenvironment (TME), play an important role in tumor progression and immunoregulation by remodeling extracellular matrix (ECM) and secreting cytokines. However, little is known about the details of the underly...

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Detalles Bibliográficos
Autores principales: Zhang, Zhao, Yu, Yongbo, Zhang, Zhilei, Li, Dan, Liang, Zhijuan, Wang, Liping, Chen, Yuanbin, Liang, Ye, Niu, Haitao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10675892/
https://www.ncbi.nlm.nih.gov/pubmed/38001512
http://dx.doi.org/10.1186/s13046-023-02900-0