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Cancer-associated fibroblasts-derived CXCL12 enhances immune escape of bladder cancer through inhibiting P62-mediated autophagic degradation of PDL1
BACKGROUND: Cancer-associated fibroblasts (CAFs), the predominant stromal cell of tumor microenvironment (TME), play an important role in tumor progression and immunoregulation by remodeling extracellular matrix (ECM) and secreting cytokines. However, little is known about the details of the underly...
Autores principales: | Zhang, Zhao, Yu, Yongbo, Zhang, Zhilei, Li, Dan, Liang, Zhijuan, Wang, Liping, Chen, Yuanbin, Liang, Ye, Niu, Haitao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10675892/ https://www.ncbi.nlm.nih.gov/pubmed/38001512 http://dx.doi.org/10.1186/s13046-023-02900-0 |
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