Targeting GPR65 alleviates hepatic inflammation and fibrosis by suppressing the JNK and NF-κB pathways

BACKGROUND: G-protein coupled receptors (GPCRs) are recognized as attractive targets for drug therapy. However, it remains poorly understood how GPCRs, except for a few chemokine receptors, regulate the progression of liver fibrosis. Here, we aimed to reveal the role of GPR65, a proton-sensing recep...

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Detalles Bibliográficos
Autores principales: Zhang, Kun, Zhang, Meng-Xia, Meng, Xiao-Xiang, Zhu, Jing, Wang, Jia-Jun, He, Yi-Fan, Li, Ye-Hua, Zhao, Si-Cong, Shi, Zhe-Min, Zheng, Li-Na, Han, Tao, Hong, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10675918/
https://www.ncbi.nlm.nih.gov/pubmed/38001521
http://dx.doi.org/10.1186/s40779-023-00494-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10675918/
https://www.ncbi.nlm.nih.gov/pubmed/38001521
http://dx.doi.org/10.1186/s40779-023-00494-4

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