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Role of arachidonic acid metabolism in intervertebral disc degeneration: identification of potential biomarkers and therapeutic targets via multi-omics analysis and artificial intelligence strategies

BACKGROUND: Intervertebral disc degeneration (IVDD) is widely recognized as the primary etiological factor underlying low back pain, often necessitating surgical intervention as the sole recourse in severe cases. The metabolic pathway of arachidonic acid (AA), a pivotal regulator of inflammatory res...

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Detalles Bibliográficos
Autores principales: Tan, Jianye, Shi, Meiling, Li, Bin, Liu, Yuan, Luo, Shengzhong, Cheng, Xigao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10675942/
https://www.ncbi.nlm.nih.gov/pubmed/38007425
http://dx.doi.org/10.1186/s12944-023-01962-5