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IFN-γ in ovarian tumor microenvironment upregulates HLA-E expression and predicts a poor prognosis

BACKGROUND: Inflammation and immunity are two main characteristics of tumor microenvironment (TME). Interferon-gamma (IFN-γ) is generally considered as a pro-inflammatory cytokine which mediates anti-tumor immune response. Recently, IFN-γ was also reported to play a protumorigenic role. However, the...

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Detalles Bibliográficos
Autores principales: Zheng, Hui, Guan, Xiaolin, Meng, Xin, Tong, Ying, Wang, Yanchun, Xie, Suhong, Guo, Lin, Lu, Renquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10675946/
https://www.ncbi.nlm.nih.gov/pubmed/38007483
http://dx.doi.org/10.1186/s13048-023-01286-z