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Gut microbiota-bile acid crosstalk regulates murine lipid metabolism via the intestinal FXR-FGF19 axis in diet-induced humanized dyslipidemia

BACKGROUND: Diet-induced dyslipidemia is linked to the gut microbiota, but the causality of microbiota-host interaction affecting lipid metabolism remains controversial. Here, the humanized dyslipidemia mice model was successfully built by using fecal microbiota transplantation from dyslipidemic don...

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Detalles Bibliográficos
Autores principales: Xu, Hongtao, Fang, Fang, Wu, Kaizhang, Song, Jiangping, Li, Yaqian, Lu, Xingyu, Liu, Juncheng, Zhou, Liuyang, Yu, Wenqing, Yu, Fei, Gao, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10675972/
https://www.ncbi.nlm.nih.gov/pubmed/38001551
http://dx.doi.org/10.1186/s40168-023-01709-5