Metabolomic analyses uncover an inhibitory effect of niclosamide on mitochondrial membrane potential in cholangiocarcinoma cells

BACKGROUND: Niclosamide is an oral anthelminthic drug that has been used for treating tapeworm infections. Its mechanism involves the disturbance of mitochondrial membrane potential that in turn inhibits oxidative phosphorylation leading to ATP depletion. To date, niclosamide has been validated as t...

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Detalles Bibliográficos
Autores principales: Kulthawatsiri, Thanaporn, Kittirat, Yingpinyapat, Phetcharaburanin, Jutarop, Tomacha, Jittima, Promraksa, Bundit, Wangwiwatsin, Arporn, Klanrit, Poramate, Titapun, Attapol, Loilome, Watcharin, Namwat, Nisana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2023
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10676079/
https://www.ncbi.nlm.nih.gov/pubmed/38025687
http://dx.doi.org/10.7717/peerj.16512

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10676079/
https://www.ncbi.nlm.nih.gov/pubmed/38025687
http://dx.doi.org/10.7717/peerj.16512

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