APOE4 expression confers a mild, persistent reduction in neurovascular function in the visual cortex and hippocampus of awake mice

Vascular factors are known to be early and important players in Alzheimer’s disease (AD) development, however the role of the ε4 allele of the Apolipoprotein (APOE) gene (a risk factor for developing AD) remains unclear. APOE4 genotype is associated with early and severe neocortical vascular deficit...

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Detalles Bibliográficos
Autores principales: Bonnar, Orla, Shaw, Kira, Anderle, Silvia, Grijseels, Dori M, Clarke, Devin, Bell, Laura, King, Sarah L, Hall, Catherine N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10676141/
https://www.ncbi.nlm.nih.gov/pubmed/37350319
http://dx.doi.org/10.1177/0271678X231172842

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10676141/
https://www.ncbi.nlm.nih.gov/pubmed/37350319
http://dx.doi.org/10.1177/0271678X231172842

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