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Effect of Tucatinib on Cardiac Repolarization in Healthy Volunteers

BACKGROUND AND OBJECTIVE: Tucatinib is a selective tyrosine kinase inhibitor of the human epidermal growth factor receptor 2 (HER2) approved to treat metastatic HER2-positive breast and colorectal cancers. The International Council for Harmonisation of Technical Requirements for Human Use (ICH) E14...

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Detalles Bibliográficos
Autores principales: Topletz-Erickson, Ariel R., Mayor, JoAl G., Liu, Hsu-Tai, Abdulrasool, Layth I., Endres, Christopher J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10676329/
https://www.ncbi.nlm.nih.gov/pubmed/37751113
http://dx.doi.org/10.1007/s40268-023-00440-8