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Improvement of the conjugation transfer of N. gerenzanensis based on the synergistic effect of quorum sensing and antibiotic interference

Nonomuraea gerenzanensis (N. gerenzanensis) is known for its ability to biosynthesize A40926, the precursor of the glycopeptide antibiotic (GPA) Dalbavancin. However, challenges and uncertainties related to the genetic manipulation of the rare actinomycetes remain. In order to improve the conjugatio...

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Detalles Bibliográficos
Autores principales: shi, Shi, Cheng, Yutong, Wang, Shuai, Zhang, Xiangmei, Han, Fubo, Li, Xiaojing, Dong, Huijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10676335/
https://www.ncbi.nlm.nih.gov/pubmed/38006456
http://dx.doi.org/10.1186/s13568-023-01641-9