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Core-dependent post-translational modifications guide the biosynthesis of a new class of hypermodified peptides

The ribosomally synthesized and post-translationally modified peptide (RiPPs) class of natural products has undergone significant expansion due to the rapid growth in genome sequencing data. Using a bioinformatics approach, we identify the dehydrazoles, a novel class of hypermodified RiPPs that cont...

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Detalles Bibliográficos
Autores principales: Pei, Zeng-Fei, Zhu, Lingyang, Nair, Satish K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10676384/
https://www.ncbi.nlm.nih.gov/pubmed/38007494
http://dx.doi.org/10.1038/s41467-023-43604-5