Vascular dysfunction caused by loss of Brn-3b/POU4F2 transcription factor in aortic vascular smooth muscle cells is linked to deregulation of calcium signalling pathways

Phenotypic and functional changes in vascular smooth muscle cells (VSMCs) contribute significantly to cardiovascular diseases (CVD) but factors driving early adverse vascular changes are poorly understood. We report on novel and important roles for the Brn-3b/POU4F2 (Brn-3b) transcription factor (TF...

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Detalles Bibliográficos
Autores principales: Yogendran, Vaishaali, Mele, Laura, Prysyazhna, Oleksandra, Budhram-Mahadeo, Vishwanie S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10676411/
https://www.ncbi.nlm.nih.gov/pubmed/38007517
http://dx.doi.org/10.1038/s41419-023-06306-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10676411/
https://www.ncbi.nlm.nih.gov/pubmed/38007517
http://dx.doi.org/10.1038/s41419-023-06306-w

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