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Vascular dysfunction caused by loss of Brn-3b/POU4F2 transcription factor in aortic vascular smooth muscle cells is linked to deregulation of calcium signalling pathways
Phenotypic and functional changes in vascular smooth muscle cells (VSMCs) contribute significantly to cardiovascular diseases (CVD) but factors driving early adverse vascular changes are poorly understood. We report on novel and important roles for the Brn-3b/POU4F2 (Brn-3b) transcription factor (TF...
Autores principales: | Yogendran, Vaishaali, Mele, Laura, Prysyazhna, Oleksandra, Budhram-Mahadeo, Vishwanie S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10676411/ https://www.ncbi.nlm.nih.gov/pubmed/38007517 http://dx.doi.org/10.1038/s41419-023-06306-w |
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