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Simvastatin-Loaded Nanostructured Lipid Carriers as Topical Drug Delivery System for Wound Healing Purposes: Preparation, Characterization, and In Vivo Histopathological Studies

PURPOSE: Simvastatin, a 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor, is a commonly used drug to reduce total cholesterol and low-density lipoprotein (LDL) levels. Furthermore, several mechanisms showed the wound-healing potential of statins, especially simvastatin. Simvastati...

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Detalles Bibliográficos
Autores principales: Mousavi-Simakani, Seyedeh Maryam, Azadi, Amir, Tanideh, Nader, Omidifar, Navid, Ghasemiyeh, Parisa, Mohammadi-Samani, Soliman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tabriz University of Medical Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10676542/
https://www.ncbi.nlm.nih.gov/pubmed/38022815
http://dx.doi.org/10.34172/apb.2023.083