Cargando…

Expression and Biological Evaluation of an Engineered Recombinant L-asparaginase Designed by In Silico Method Based on Sequence of the Enzyme from Escherichia coli

PURPOSE: Medical usage of L-asparaginase (ASNase), the first-line of acute lymphoblastic leukemia treatment, is linked to allergic responses and toxicities, which necessitates the development of new bio-better ASNases. The aim of the current study was in silico design of a novel ASNase with predicte...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dastmalchi, Mahrokh, Alizadeh, Mahdiyeh, Jamshidi-Kandjan, Omid, Rezazadeh, Hassan, Hamzeh-Mivehroud, Maryam, Farajollahi, Mohammad M, Dastmalchi, Siavoush
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Tabriz University of Medical Sciences 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10676546/ https://www.ncbi.nlm.nih.gov/pubmed/38022803 http://dx.doi.org/10.34172/apb.2023.085

Ejemplares similares

Highly efficient novel recombinant L-asparaginase with no glutaminase activity from a new halo-thermotolerant Bacillus strain
por: Safary, Azam, et al.
Publicado: (2019)

A Simple and Rapid Protocol for Producing Yeast Extract from Saccharomyces cerevisiae Suitable for Preparing Bacterial Culture Media
por: Zarei, Omid, et al.
Publicado: (2016)

Identification of Novel Mutations in Arabidopsis thaliana DOF 4.2 Coding Gene
por: Jamshidi Kandjani, Omid, et al.
Publicado: (2021)

Characterizing the Hot Spots Involved in RON-MSPβ Complex Formation Using In Silico Alanine Scanning Mutagenesis and Molecular Dynamics Simulation
por: Zarei, Omid, et al.
Publicado: (2017)

In silico Evaluation of Crosslinking Effects on Denaturant m (eq) values and ΔCp upon Protein Unfolding
por: Hamzeh-Mivehroud, Maryam, et al.
Publicado: (2012)

In-silico Investigation of Tubulin Binding Modes of a Series of Novel Antiproliferative Spiroisoxazoline Compounds Using Docking Studies
por: Abolhasani, Hoda, et al.
Publicado: (2015)

Comparison of Different 2D and 3D-QSAR Methods on Activity Prediction of Histamine H3 Receptor Antagonists
por: Dastmalchi, Siavoush, et al.
Publicado: (2012)

An Alignment-Independent 3D-QSAR Study of FGFR2 Tyrosine Kinase Inhibitors
por: Jafari, Behzad, et al.
Publicado: (2017)

Drug Repurposing for Identification of S1P1 Agonists with Potential Application in Multiple Sclerosis Using In Silico Drug Design Approaches
por: Alizadeh, Ali Akbar, et al.
Publicado: (2023)

Expression, Purification and Characterization of Functional Teduglutide Using GST Fusion System in Prokaryotic Cells
por: Alizadeh, Ali Akbar, et al.
Publicado: (2023)

Characterization of Novel Fragment Antibodies Against TNF-alpha Isolated Using Phage Display Technique
por: Alizadeha, Ali Akbar, et al.
Publicado: (2019)

Expression, purification and DNA-binding properties of zinc finger domains of DOF proteins from Arabidopsis thaliana
por: Moghaddas Sani, Hakimeh, et al.
Publicado: (2018)

Alignment independent 3D-QSAR studies and molecular dynamics simulations for the identification of potent and selective S1P(1) receptor agonists
por: Alizadeh, Ali Akbar, et al.
Publicado: (2020)

A QSAR Study on the 4-Substituted Coumarins as Potent Tubulin Polymerization Inhibitors
por: Dinparast, Leila, et al.
Publicado: (2020)

Application of Carbonic Nanosheets Based on Urea Precursors as Dispersive Solid Phase Extraction Adsorbent for Extraction of Methamphetamine from Urine Samples
por: Taghvimi, Arezou, et al.
Publicado: (2021)

Preparation and Antiproliferative Activity Evaluation of Juglone-Loaded BSA Nanoparticles
por: Jahanban-Esfahlan, Ali, et al.
Publicado: (2022)

Characterization of Shiga toxin-producing Escherichia coli (STEC) in feces of healthy and diarrheic calves in Urmia region, Iran
por: Dastmalchi, Saei H, et al.
Publicado: (2012)

Modelling the structures of G protein-coupled receptors aided by three-dimensional validation
por: Dastmalchi, Siavoush, et al.
Publicado: (2008)

Systems biology comprehensive analysis on breast cancer for identification of key gene modules and genes associated with TNM-based clinical stages
por: Amjad, Elham, et al.
Publicado: (2020)

Prediction of the Human EP1 Receptor Binding Site by Homology Modeling and Molecular Dynamics Simulation
por: Zare, Behnoush, et al.
Publicado: (2011)

Clinical Application Study of Polymeric Nanospheres Network in Methylphenidate Extraction from Urine Samples by Dispersive Solid Phase Extraction Adsorbent
por: Taghvimi, Arezou, et al.
Publicado: (2022)

Quality comparison of a state-of-the-art preparation of a recombinant L-asparaginase derived from Escherichia coli with an alternative asparaginase product
por: Schnuchel, Arndt, et al.
Publicado: (2023)

Design and Construction of a Novel Humanized Single-Chain Variable-Fragment Antibody Against the Tumor Necrosis Factor Alpha
por: Farajzadeh, Davoud, et al.
Publicado: (2019)

Comparison of 4-chloro-2-nitrophenol adsorption on single-walled and multi-walled carbon nanotubes
por: Mehrizad, Ali, et al.
Publicado: (2012)

Effect of Different Additives on Genotoxicity of Mineral Trioxide Aggregate
por: Samiei, Mohammad, et al.
Publicado: (2018)

Development of Escherichia coli asparaginase II for the Treatment of Acute Lymphocytic Leukemia: In Silico Reduction of asparaginase II Side Effects by a Novel Mutant (V27F)
por: Ardalan, Noeman, et al.
Publicado: (2021)

Recombinant L-Asparaginase from Zymomonas mobilis: A Potential New Antileukemic Agent Produced in Escherichia coli
por: Einsfeldt, Karen, et al.
Publicado: (2016)

PEG-asparaginase and native Escherichia coli L-asparaginase in acute lymphoblastic leukemia in children and adolescents: a systematic review
por: Medawar, Camile Valle, et al.
Publicado: (2020)

Correction: Recombinant L-Asparaginase from Zymomonas mobilis: A Potential New Antileukemic Agent Produced in Escherichia coli
por: Einsfeldt, Karen, et al.
Publicado: (2016)

Development of Processes for Recombinant L-Asparaginase II Production by Escherichia coli Bl21 (De3): From Shaker to Bioreactors
por: Barros, Thaís, et al.
Publicado: (2020)

Cloning, expression, purification and characterisation of Erwinia carotovora L-asparaginase in Escherichia coli
por: Pourhossein, Meraj, et al.
Publicado: (2014)

SUPPRESSION OF MURINE LEUKEMIAS BY L-ASPARAGINASE : INCIDENCE OF SENSITIVITY AMONG LEUKEMIAS OF VARIOUS TYPES: COMPARATIVE INHIBITORY ACTIVITIES OF GUINEA PIG SERUML-ASPARAGINASE AND ESCHERICHIA COLI L-ASPARAGINASE
por: Boyse, Edward A., et al.
Publicado: (1967)

Noncompetitive Inhibition of Bovine Liver Catalase by Lawsone: Kinetics, Binding Mechanism and in silico Modeling Approaches
por: khataee, Simin, et al.
Publicado: (2020)

17β-Estradiol-Loaded Exosomes for Targeted Drug Delivery in Osteoporosis: A Comparative Study of Two Loading Methods
por: Gholami Farashah, Mohammad Sadegh, et al.
Publicado: (2023)

6D-QSAR for predicting biological activity of human aldose reductase inhibitors using quasar receptor surface modeling
por: Sokouti, Babak, et al.
Publicado: (2023)

Recombinant L-asparaginase 1 from Saccharomyces cerevisiae: an allosteric enzyme with antineoplastic activity
por: Costa, Iris Munhoz, et al.
Publicado: (2016)

Biochemical and Biological Evaluation of an L-Asparaginase from Isolated Escherichia coli MF-107 as an Anti-Tumor Enzyme on MCF7 Cell Line
por: Shahnazari, Masoumeh, et al.
Publicado: (2022)

In Silico Design of a Chimeric Humanized L-asparaginase
por: Pedroso, Alejandro, et al.
Publicado: (2023)

Comparison of Native Escherichia coli L-Asparaginase versus Pegylated Asparaginase, in Combination with Ifosfamide, Methotrexate, Etoposide, and Prednisolone, in Extranodal NK/T-Cell Lymphoma, Nasal Type
por: Kim, Hyun Jee, et al.
Publicado: (2018)

Protection of renal damage by HMG-CoA inhibitors: A comparative study between atorvastatin and rosuvastatin
por: Jabarpour, Maryam, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_fpdnm2huqcllu68ft64bvhld87