The survivin-ran inhibitor LLP-3 decreases oxidative phosphorylation, glycolysis and growth of neuroblastoma cells

BACKGROUND: Neuroblastoma (NB), the most common extracranial solid malignancy in children, carries a poor prognosis in high-risk disease, thus requiring novel therapeutic approaches. Survivin is overexpressed in NB, has pro-mitotic and anti-apoptotic functions, and impacts on oxidative phosphorylati...

Descripción completa

Detalles Bibliográficos
Autores principales: Galiger, Celimene, Zohora, Fatema Tuj, Dorneburg, Carmen, Tews, Daniel, Debatin, Klaus-Michael, Beltinger, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10676583/
https://www.ncbi.nlm.nih.gov/pubmed/38007466
http://dx.doi.org/10.1186/s12885-023-11635-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10676583/
https://www.ncbi.nlm.nih.gov/pubmed/38007466
http://dx.doi.org/10.1186/s12885-023-11635-2

Ejemplares similares