ALKBH5-mediated CHAC1 depletion promotes malignant progression and decreases cisplatin-induced oxidative stress in gastric cancer

The m6a demethyltransferase ALKBH5 dynamically modulates gene expression and intracellular metabolic molecules by modifying RNA m6a in cancer cells. However, ALKBH5’s function in gastric cancer (GC) has remained controversial. This study demonstrates that ALKBH5 is highly expressed in GC. Silencing...

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Detalles Bibliográficos
Autores principales: Chen, Chunting, Zhai, Ertao, Liu, Yinan, Qian, Yan, Zhao, Risheng, Ma, Yan, Liu, Jianqiu, Huang, Zhixin, Chen, Jianhui, Cai, Shirong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10676604/
https://www.ncbi.nlm.nih.gov/pubmed/38007439
http://dx.doi.org/10.1186/s12935-023-03129-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10676604/
https://www.ncbi.nlm.nih.gov/pubmed/38007439
http://dx.doi.org/10.1186/s12935-023-03129-9

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