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USP7 Inhibits Osteoclastogenesis via Dual Effects of Attenuating TRAF6/TAK1 Axis and Stimulating STING Signaling

Ubiquitination is a reversible post-translational modification implicated in cell differentiation, homeostasis, and organ development. Several deubiquitinases (DUBs) decrease protein ubiquitination through the hydrolysis of ubiquitin linkages. However, the role of DUBs in bone resorption and formati...

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Detalles Bibliográficos
Autores principales: Xie, Ziang, Wu, Yizheng, Shen, Yang, Guo, Jiandong, Yuan, Putao, Ma, Qingliang, Wang, Shiyu, Jie, Zhiwei, Zhou, Hongyi, Fan, Shunwu, Chen, Shuai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JKL International LLC 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10676781/
https://www.ncbi.nlm.nih.gov/pubmed/37199589
http://dx.doi.org/10.14336/AD.2023.0325-1