Huntingtin Decreases Susceptibility to a Spontaneous Seizure Disorder in FVN/B Mice

Huntington disease (HD) is an adult-onset neurodegenerative disorder that is caused by a trinucleotide CAG repeat expansion in the HTT gene that codes for the protein huntingtin (HTT in humans or Htt in mice). HTT is a multi-functional, ubiquitously expressed protein that is essential for embryonic...

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Detalles Bibliográficos
Autores principales: Van Raamsdonk, Jeremy M., Al-Shekaili, Hilal H., Wagner, Laura, Bredy, Tim W, Chan, Laura, Pearson, Jacqueline, Schwab, Claudia, Murphy, Zoe, Devon, Rebecca S., Lu, Ge, Kobor, Michael S., Hayden, Michael R., Leavitt, Blair R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JKL International LLC 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10676795/
https://www.ncbi.nlm.nih.gov/pubmed/37199581
http://dx.doi.org/10.14336/AD.2023.0423

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10676795/
https://www.ncbi.nlm.nih.gov/pubmed/37199581
http://dx.doi.org/10.14336/AD.2023.0423

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