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IFNγ Transcribed by IRF1 in CD4(+) Effector Memory T Cells Promotes Senescence-Associated Pulmonary Fibrosis

Physiologically aged lungs are prone to senescence-associated pulmonary diseases (SAPD). This study aimed to determine the mechanism and subtype of aged T cells affecting alveolar type II epithelial (AT2) cells, which promote the pathogenesis of senescence-associated pulmonary fibrosis (SAPF). Cell...

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Detalles Bibliográficos
Autores principales: Chen, Haiyun, Wang, Qiuyi, Li, Jie, Li, Yuan, Chen, Ao, Zhou, Jiawen, Zhao, Jingyu, Mao, Zhiyuan, Zhou, Zihao, Zhang, Jin’ge, Wang, Yue, Wang, Rong, Li, Qing, Zhang, Yongjie, Jiang, Runqiu, Miao, Dengshun, Jin, Jianliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JKL International LLC 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10676796/
https://www.ncbi.nlm.nih.gov/pubmed/37199578
http://dx.doi.org/10.14336/AD.2023.0320