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283. Screening the PE/PPE secreted effectors of Mycobacterium tuberculosis to uncover novel virulence-promoting genes

BACKGROUND: Mycobacterium tuberculosis (M.tb) remains the leading cause of infectious disease mortality, with over 10 million active cases and 1.5 million deaths annually at the global scale. Although M.tb infection prompts highly inflammatory granulomatous lesions in the lung, the bacterium is not...

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Detalles Bibliográficos
Autores principales: Koleske, Benjamin, Shen, Jessica, Gupta, Manish, Bishai, William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10677226/
http://dx.doi.org/10.1093/ofid/ofad500.355