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1348. Identification of GB-0669, a Novel S-2 Targeted Spike Monoclonal Antibody in Development for SARS-CoV-2 Prophylaxis

BACKGROUND: The clinical benefit of anti-spike mAbs for prophylaxis and treatment of SARS-CoV-2 is now well established (Baum 2020, Loo 2022, Westendorf 2022, Jones 2021, Kreuzberger 2021, Cathcart 2021, Hirsch 2022, Shi 2020); However, the evolution of SARS CoV-2 due to immune pressure has compromi...

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Detalles Bibliográficos
Autores principales: Borriello, Francesco, Marden, Grace, Li, Hongru, Carlin, Eric, Sharma, Geetika, Menzenski, Monica, Jecrois, Anne, Palovcak, Eugene, Lord, Dana, Tao, Jenhan, Grigoryan, Gevorg, Root, Adam, Hopson, Kristen, Hazuda, Daria, Van Epps, Heather A, Ramos, Alex, Joh, Nathan H, Russell, Pamela, Garlick, Joseph D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10677384/
http://dx.doi.org/10.1093/ofid/ofad500.1185