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2066. Synergistic Bacteriophage-Antibiotic Combinations Against High Inoculum DNS MRSA

BACKGROUND: Phage-antibiotic combinations (PAC) have been proposed for high inoculum daptomycin-nonsusceptible (DNS) MRSA infections refractory to conventional therapy. We studied PAC with synergistic activity against two DNS MRSA clinical bloods isolates (C4 and C37; DAP MIC = 4 ug/mL). METHODS: PA...

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Detalles Bibliográficos
Autores principales: Kunz Coyne, Ashlan J, Stamper, Kyle, Bleick, Callan, Bayer, Arnold S, Lehman, Susan, Rybak, Michael J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10677425/
http://dx.doi.org/10.1093/ofid/ofad500.136