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2156. The Rational Design of SER-147: a Cultivated Microbial Consortium to Restore Colonization Resistance and Mitigate Infection in Chronic Liver Disease

BACKGROUND: Chronic liver disease (CLD) is a major cause of morbidity and mortality, with high risk of infection as CLD progresses. Gut microbiome disruption, which worsens with CLD severity, causes loss of colonization resistance and impaired gastrointestinal (GI) barrier function, enabling pathoge...

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Detalles Bibliográficos
Autores principales: Wurster, Jenna, Straub, Tim, O’Brien, Edward J, Ennis, Nathaniel J, Mayol, Melissa, Brown, Jessica, Vulić, Marin, Beauchemin, Nicholas, Halvorsen, Elizabeth, Ford, Christopher, Henn, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10677428/
http://dx.doi.org/10.1093/ofid/ofad500.1779