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2156. The Rational Design of SER-147: a Cultivated Microbial Consortium to Restore Colonization Resistance and Mitigate Infection in Chronic Liver Disease
BACKGROUND: Chronic liver disease (CLD) is a major cause of morbidity and mortality, with high risk of infection as CLD progresses. Gut microbiome disruption, which worsens with CLD severity, causes loss of colonization resistance and impaired gastrointestinal (GI) barrier function, enabling pathoge...
Autores principales: | Wurster, Jenna, Straub, Tim, O’Brien, Edward J, Ennis, Nathaniel J, Mayol, Melissa, Brown, Jessica, Vulić, Marin, Beauchemin, Nicholas, Halvorsen, Elizabeth, Ford, Christopher, Henn, Matthew |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10677428/ http://dx.doi.org/10.1093/ofid/ofad500.1779 |
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