2062. In Vivo Efficacy of CD388, a Novel Drug Fc-Conjugate (DFC), Against Seasonal Subtypes of Influenza in Prophylaxis in Immune Competent Mice, and in a Severe Immunodeficient (SCID) Mouse Model

BACKGROUND: Influenza remains a significant public health concern due to the limited efficacy of vaccines. Cidara has developed CD388, a multivalent conjugate of a dimeric neuraminidase inhibitor with a proprietary hIgG1 Fc domain engineered for extended half-life, currently in clinical development....

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Detalles Bibliográficos
Autores principales: Levin, James, Döhrmann, Simon, Cole, Jason N, Amundson, Karin, Borchardt, Allen, Brady, Thomas P, Lam, Thanh, Fortier, Joanne, Almaguer, Amanda, Tari, Leslie W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Abstract
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10677641/
http://dx.doi.org/10.1093/ofid/ofad500.132

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10677641/
http://dx.doi.org/10.1093/ofid/ofad500.132

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