314. Using CRISPR/Cas9 to dissect the regions of MLL/AF9 that are critical for myeloid immortalization

BACKGROUND: High volumes of neutrophils are required for the successful granulocyte transfusion. Our goal is to expand neutrophil progenitors ex vivo to provide white blood cell transfusions of sufficient cell number. Creating a conditionally immortalized granulocyte-monocyte progenitor (GMP) would...

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Detalles Bibliográficos
Autores principales: Yvanovich, Emma, Timmer, Kyle, Mansour, Michael, Sykes, David B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Abstract
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10677674/
http://dx.doi.org/10.1093/ofid/ofad500.385

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10677674/
http://dx.doi.org/10.1093/ofid/ofad500.385

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