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314. Using CRISPR/Cas9 to dissect the regions of MLL/AF9 that are critical for myeloid immortalization
BACKGROUND: High volumes of neutrophils are required for the successful granulocyte transfusion. Our goal is to expand neutrophil progenitors ex vivo to provide white blood cell transfusions of sufficient cell number. Creating a conditionally immortalized granulocyte-monocyte progenitor (GMP) would...
Autores principales: | Yvanovich, Emma, Timmer, Kyle, Mansour, Michael, Sykes, David B |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10677674/ http://dx.doi.org/10.1093/ofid/ofad500.385 |
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