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2065. Efficacy of D-peptide-conjugated Antisense Compounds Against Pseudomonas aeruginosa

BACKGROUND: Pseudomonas aeruginosa (PA) causes significant morbidity and mortality in immunocompromised hosts and those with cystic fibrosis. Peptide-conjugated phosphorodiamidate morpholino oligomers (PPMOs) are antisense compounds designed to target specific genes and prevent translation. PPMOs wi...

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Detalles Bibliográficos
Autores principales: Koch, Rachelle E, Moustafa, Dina A, Pybus, Christine A, Goldberg, Joanna B, Greenberg, David E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10677789/
http://dx.doi.org/10.1093/ofid/ofad500.135