2569. Pharmacokinetic-Pharmacodynamic Evaluation of Sulopenem Using a Five-Day Hollow-Fiber In Vitro Infection Model

BACKGROUND: Sulopenem etzadroxil, the oral (PO) prodrug of the active moiety sulopenem, is a thiopenem in development for the treatment of uncomplicated urinary tract infection (uUTI). Oral sulopenem is a bilayer tablet composed of sulopenem etzadroxil and probenecid, an organic anion transport inhi...

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Detalles Bibliográficos
Autores principales: VanScoy, Brian D, Conde, Haley, Vincent, Catherine E, Bhavnani, Sujata M, Aronin, Steven I, Puttagunta, Sailaja, Ambrose, Paul G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Abstract
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10677872/
http://dx.doi.org/10.1093/ofid/ofad500.2186

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10677872/
http://dx.doi.org/10.1093/ofid/ofad500.2186

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