Cargando…

2176. Cardiolipin Synthases Play Redundant Roles And Are Required for Membrane Remodeling in Daptomycin Resistant Enterococcus faecalis

BACKGROUND: Daptomycin (DAP) is a lipopeptide antibiotic targeting anionic phospholipids (APLs) at the division septum. Resistance to DAP (DAP-R) in E. faecalis (Efs) has been associated with activation of the LiaFSR response and redistribution of APL microdomains through the effector protein LiaX....

Descripción completa

Detalles Bibliográficos
Autores principales: Nguyen, April, Tran, Truc, Panesso, Diana, Hood, Kara S, Polamraju, Vinathi, Zhang, Rutan, Khan, Ayesha, Miller, William R, Mileykovskaya, Eugenia, Shamoo, Yousif, Xu, Libin, Vitrac, Heidi, Arias, Cesar A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10677922/
http://dx.doi.org/10.1093/ofid/ofad500.1798