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2176. Cardiolipin Synthases Play Redundant Roles And Are Required for Membrane Remodeling in Daptomycin Resistant Enterococcus faecalis
BACKGROUND: Daptomycin (DAP) is a lipopeptide antibiotic targeting anionic phospholipids (APLs) at the division septum. Resistance to DAP (DAP-R) in E. faecalis (Efs) has been associated with activation of the LiaFSR response and redistribution of APL microdomains through the effector protein LiaX....
Autores principales: | Nguyen, April, Tran, Truc, Panesso, Diana, Hood, Kara S, Polamraju, Vinathi, Zhang, Rutan, Khan, Ayesha, Miller, William R, Mileykovskaya, Eugenia, Shamoo, Yousif, Xu, Libin, Vitrac, Heidi, Arias, Cesar A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10677922/ http://dx.doi.org/10.1093/ofid/ofad500.1798 |
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