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292. Phosphorodiamidate Morpholino Oligomers Targeting acpP Reduce the Biofilm Burden in Burkholderia cepacia Complex

BACKGROUND: The Burkholderia cepacia complex (Bcc) is composed of highly related opportunistic species that establish pulmonary infections in immunodeficient hosts, such as those with cystic fibrosis and chronic granulomatous disease. Due to their innate antibiotic-resistant phenotypes and capacity...

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Detalles Bibliográficos
Autores principales: Mendez, Antonio R, Pybus, Christine A, Greenberg, David E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10678012/
http://dx.doi.org/10.1093/ofid/ofad500.364