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349. The impact of Vancomycin dosing by area under the curve over minimal inhibitory concentration (AUC/MIC) versus Trough levels on cumulative Vancomycin dosage and incidence of Acute Kidney Injury (AKI) in patients admitted to intensive care units (ICU)
BACKGROUND: Higher Vancomycin trough levels (15-20 mcg/ml) are associated with increased risk of AKI. IDSA recommends dosing Vancomycin as per AUC/MIC reduces the risk of nephrotoxicity. The aim of this study was to determine if AUC/MIC dosing could reduce the incidence of nephrotoxicity patients in...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10678022/ http://dx.doi.org/10.1093/ofid/ofad500.420 |