349. The impact of Vancomycin dosing by area under the curve over minimal inhibitory concentration (AUC/MIC) versus Trough levels on cumulative Vancomycin dosage and incidence of Acute Kidney Injury (AKI) in patients admitted to intensive care units (ICU)

BACKGROUND: Higher Vancomycin trough levels (15-20 mcg/ml) are associated with increased risk of AKI. IDSA recommends dosing Vancomycin as per AUC/MIC reduces the risk of nephrotoxicity. The aim of this study was to determine if AUC/MIC dosing could reduce the incidence of nephrotoxicity patients in...

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Detalles Bibliográficos
Autores principales: Sahu, Aniruddha, Wang, Kevin K, Jurasinski, Philip, Kulkarni, Salil, Weihs, Sayo, Mizusawa, Masako, Bamberger, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Abstract
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10678022/
http://dx.doi.org/10.1093/ofid/ofad500.420

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