2520. A Phase 1b Study of the Safety, Pharmacokinetics, and Ex Vivo Tick Killing of the Lyme Prophylaxis Candidate TP-05

BACKGROUND: In the U.S., Lyme disease is the most common vector-borne disease caused by infection with B. burgdorferi bacteria following a bite by a tick vector. TP-05 (lotilaner oral capsule), an isoxazoline, is a selective inhibitor of insect and acarine GABA mediated chloride channels, which para...

Descripción completa

Detalles Bibliográficos
Autores principales: Lim, Jeremy J, Crean, Christopher S, Partin, Hilary A, Trevejo, Jose M, Neervannan, Seshadri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Abstract
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10678042/
http://dx.doi.org/10.1093/ofid/ofad500.2138

Ejemplares similares

Ejemplares similares