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2798. Difficult to treat GES and KPC harboring Pseudomonas aeruginosa: Evaluation of in vivo efficacy of ß-lactam/ß-lactamase inhibitor humanized exposure vs. in vitro efficacy

BACKGROUND: GES and KPC harboring Pseudomonas aeruginosa (PSA) pose a challenge clinically as therapeutic alternatives are limited, and clinical data is scarce. Murine models provide translational data that can provide insight into therapeutic alternatives, and assist in clinical guidance. Herein, w...

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Detalles Bibliográficos
Autores principales: Ruiz, Victor H, Gill, Christian, Nicolau, David P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10678086/
http://dx.doi.org/10.1093/ofid/ofad500.2409