Cargando…

2130. Safety and Pharmacokinetics of SPR206 in Subjects with Varying Degrees of Renal Impairment

BACKGROUND: SPR206 is a novel polymyxin derivative with potent in vitro activity against susceptible and multidrug-resistant strains of Acinetobacter baumannii, Pseudomonas aeruginosa, Klebsiella pneumoniae, Escherichia coli, and Enterobacter species. In nonclinical studies, SPR206 had similar or gr...

Descripción completa

Detalles Bibliográficos
Autores principales: Bruss, Jon, Bader, Justin C, Hamed, Kamal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10678244/
http://dx.doi.org/10.1093/ofid/ofad500.1753