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When less is more: shortening the Lpp protein leads to increased vancomycin resistance in Escherichia coli

Vancomycin is a naturally occurring cell-wall-targeting glycopeptide antibiotic. Due to the low potency of this antibiotic against Gram-negative pathogens, such as Escherichia coli, there is a limited knowledge about interactions between vancomycin and this group of bacteria. Here, we show that an i...

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Detalles Bibliográficos
Autores principales: Wykes, Hannah, Le, Vuong Van Hung, Olivera, Catrina, Rakonjac, Jasna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Japan 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10678296/
https://www.ncbi.nlm.nih.gov/pubmed/37749219
http://dx.doi.org/10.1038/s41429-023-00658-3