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851. Metabolic Changes Contributing to Age-Associated Antifungal Tolerance in Cryptococcus neoformans
BACKGROUND: Cryptococcus neoformans (CN) is a facultative intracellular pathogen that divides asymmetrically, resulting in different phenotypes of the mother and daughter cells. After 8-10 divisions, mother cells become more resistant to phagocytic killing by macrophages and resistant to antifungals...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10678490/ http://dx.doi.org/10.1093/ofid/ofad500.896 |