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277. A Functional OMICs Evaluation of Omadacycline to Understand Anti-Clostridioides difficile Protective Effects

BACKGROUND: Omadacycline is an aminomethylcycline tetracycline with potent in vitro activity against C. difficile (CD) and a low propensity for CD infection (CDI) in clinical trials. In addition to potent in vitro activity, ideal properties of anti-CDI antibiotics include favorable effects on bile a...

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Detalles Bibliográficos
Autores principales: Jo, Jinhee, Agyapong, Samantha, Hu, Chenlin, Wang, Weiqun, Gonzales-Luna, Anne J, Lancaster, Chris, Garey, Kevin W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10678591/
http://dx.doi.org/10.1093/ofid/ofad500.349