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2568. Characterization of Sulopenem Pharmacokinetics-Pharmacodynamics Using a One-Compartment In Vitro Infection Model

BACKGROUND: Sulopenem etzadroxil, the oral (PO) prodrug of the active moiety sulopenem is a thiopenem with activity against drug-resistant pathogens known to cause uncomplicated urinary tract infection (uUTI). Oral sulopenem is a bilayer tablet composed of sulopenem etzadroxil and probenecid, an org...

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Detalles Bibliográficos
Autores principales: VanScoy, Brian D, Jones, Sean, Conde, Haley, Vincent, Catherine E, Bhavnani, Sujata M, Rubino, Christopher M, Aronin, Steven I, Puttagunta, Sailaja, Ambrose, Paul G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10678615/
http://dx.doi.org/10.1093/ofid/ofad500.2185