2141. Preclinical Evaluation of PA-001: A Novel, Potential Macrocyclic Peptide-Based Treatment for COVID-19 Which Binds to the S2 Subunit of SARS-CoV-2 Spike Protein

BACKGROUND: Despite the approval of a few COVID-19 drugs, various mutations of SARS-CoV-2 continue to emerge and pose as a threat to the efficacy of COVID-19 treatments. To address the unmet clinical need for broad-spectrum treatments, we identified and performed preclinical evaluation of PA-001, a...

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Detalles Bibliográficos
Autores principales: Kawamura, Tatsuro, Ohuchi, Masaki, Nagasawa, Takayuki, Ohashi, Hirofumi, Iwata-Yoshikawa, Naoko, Shiwa-Sudo, Nozomi, Sakai, Yusuke, Matsui, Katsuma, Matsumoto, Masatoshi, Kurasaki, Haruaki, Nagatomo, Kazutaka, Ito, Shoko, Kawamura, Naoki, Masuya, Keiichi, Nagata, Noriyo, Watashi, Koichi, Suzuki, Tadaki, Kitamura, Hidetomo, Murakami, Masato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Abstract
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10678883/
http://dx.doi.org/10.1093/ofid/ofad500.1764

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10678883/
http://dx.doi.org/10.1093/ofid/ofad500.1764

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