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2535. Physiological-based pharmacokinetic analysis of drug–drug interactions between isavuconazole and vincristine in pediatric subjects

BACKGROUND: Invasive fungal diseases (IFD), including invasive aspergillosis (IA) and invasive mucormycosis (IM), occur primarily in immunocompromised and/or hospitalized pediatric patients and are associated with morbidity and mortality. Pediatric patients being treated for leukemia with vincristin...

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Detalles Bibliográficos
Autores principales: Choules, Mary P, Otsuka, Yukio, Kovanda, Laura, Bonate, Peter, Sinnar, Shamim, Desai, Amit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10679012/
http://dx.doi.org/10.1093/ofid/ofad500.2152