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Hypoxia-induced PLOD2 promotes clear cell renal cell carcinoma progression via modulating EGFR-dependent AKT pathway activation

Clear cell renal cell carcinoma (ccRCC) is a type of kidney cancer that is both common and aggressive, with a rising incidence in recent decades. Hypoxia is a key factor that plays a vital role in the tumorigenesis and metastasis of malignancy. However, the precise mechanisms of hypoxia driving ccRC...

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Detalles Bibliográficos
Autores principales: Liu, Tao, Xiang, Wan, Chen, Zhizhuang, Wang, Gang, Cao, Rui, Zhou, Fenfang, Meng, Zhe, Luo, Yongwen, Chen, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10679098/
https://www.ncbi.nlm.nih.gov/pubmed/38008826
http://dx.doi.org/10.1038/s41419-023-06298-7