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Sequential vaccinations with divergent H1N1 influenza virus strains induce multi-H1 clade neutralizing antibodies in swine

Vaccines that protect against any H1N1 influenza A virus strain would be advantageous for use in pigs and humans. Here, we try to induce a pan-H1N1 antibody response in pigs by sequential vaccination with antigenically divergent H1N1 strains. Adjuvanted whole inactivated vaccines are given intramusc...

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Detalles Bibliográficos
Autores principales: Van Reeth, Kristien, Parys, Anna, Gracia, José Carlos Mancera, Trus, Ivan, Chiers, Koen, Meade, Philip, Liu, Sean, Palese, Peter, Krammer, Florian, Vandoorn, Elien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10679120/
https://www.ncbi.nlm.nih.gov/pubmed/38008801
http://dx.doi.org/10.1038/s41467-023-43339-3