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2163. Prevalence and geographic distribution of mutations in TonB-dependent receptors in the Prospective Observational Pseudomonas aeruginosa (PA) Study

BACKGROUND: Cefiderocol (FDC) is a last line treatment for carbapenem-resistant Pseudomonas aeruginosa (CR-PA). FDC retains activity against CR-PA by inhibition of penicillin-binding proteins facilitated by active uptake of drug via TonB-dependent receptors (TBDR). Prior, we have shown an associatio...

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Detalles Bibliográficos
Autores principales: Egge, Stephanie, Baptista, Rodrigo de Paula, Arias, Cesar A, Tam, Vincent, Satlin, Michael J, Miller, William R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10679181/
http://dx.doi.org/10.1093/ofid/ofad500.1786