383. Pharmacokinetics and Safety in Healthy Adults of RSM01, a Novel RSV Monoclonal Antibody, and Population PK Modeling to Support Pediatric Development

BACKGROUND: RSV is a common cause of infant respiratory infection and hospitalization. RSM01 is a novel anti-RSV mAb targeting the F glycoprotein essential for viral entry with a YTE mutation for half-life extension. Phase 1a PK and safety results are presented, along with an adult population PK mod...

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Detalles Bibliográficos
Autores principales: Levi, Micha, Watson, Shayne, Anderson, Aparna B, Taylor, Dale, White, Joleen T, Stamm, Luisa M, Dunne, Michael W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Abstract
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10679292/
http://dx.doi.org/10.1093/ofid/ofad500.453

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10679292/
http://dx.doi.org/10.1093/ofid/ofad500.453

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